Neurotoxin  /  Dosing & Duration
Neurotoxin Dosing · Denver, Colorado

Dose is duration.

The most common thing we correct isn’t bad injecting — it’s under-dosing. Here’s what less product actually buys you, what resistance really is, and why treating only your forehead is what ages your lower face.

Dose = Duration

Baby tox is working against you.

The most common thing we correct isn’t bad injecting — it’s under-dosing. Move the slider and watch what less product actually buys you.

Baby tox
Less productFull dose
How long it lasts6–8 weeks
How well it worksPartial

Six to eight weeks, if you’re lucky.

Neurotoxin resistance is real. Your immune system can learn to recognize and neutralize the toxin, and chronic under-dosing with frequent top-ups is one of the ways it happens. If yours has stopped working, Xeomin is usually where we start — and we go up, not down.

Full Face & Neck

A face should age synchronously.

Most people treat the top third and stop. Ten years on, the forehead is smooth and nothing below it is — and that mismatch is far more noticeable than the lines would have been. Toggle between the two approaches.

A visible disconnect

The forehead and eyes stay smooth while everything below keeps moving and folding. The two halves of your face stop matching — and that mismatch reads more clearly than the lines ever would have.

The lower face goes lax

Untreated muscles keep pulling downward, year after year. That constant downward pull is what softens a jawline long before gravity gets the blame.

Marionette lines set in

The lines running from the corners of the mouth toward the chin deepen, then stay put — visible even when your face is completely at rest.

Chin dimpling and jowling

The chin develops a pebbled, orange-peel texture from an overactive mentalis, and the jawline loses its clean edge.

The neck gives you away

Platysmal bands tighten and the neck skin loosens — the “turkey neck” that no amount of forehead tox will ever fix.

Our recommendation: full face and neck neurotoxin every six months, with your usual upper-face treatments in between. Preventative lower-face treatment from your mid-thirties is the single best thing you can do for your jawline.

Good Questions

Everything you're wondering.

Not the way it is marketed. Dose is duration. Under-dosing does not give you a subtler result that lasts just as long, it gives you a weaker result that wears off sooner, so you are back within two months paying again for the same area. Worse, repeated low-dose exposure is one of the ways patients develop resistance to neurotoxin. If you want a softer look, that comes from where the product is placed and which muscles are left alone, not from shorting the dose.

Some patients develop antibodies that neutralize the toxin, so treatments that used to last three or four months stop working. Chronic under-dosing and very frequent low-dose top-ups are risk factors. We cannot remove antibodies that already exist, but we can change strategy: Xeomin is stripped of the accessory proteins the immune system tends to react to, so it frequently still works when other toxins have stopped. We also lengthen the interval between treatments and dose properly rather than repeatedly under-dosing.

Three to four months in the face when it is properly dosed, and often longer with Daxxify. Under-dosed treatment commonly fades at six to eight weeks. Metabolism matters too: if you train hard you will clear it faster, which is exactly why we reach for Dysport in athletes. Over years of consistent, well-dosed treatment the muscles get progressively weaker, and many long-term patients end up needing less product less often.

Because a face should age synchronously. Treating only the upper face leaves you with a smooth forehead and a lower face that keeps folding, and the disconnect between the two becomes more obvious than the original lines. Over time the untreated lower face becomes lax, marionette lines form, chin dimpling and jowling become more prominent, and the neck skin loosens into what people call turkey neck. Starting preventative lower-face neurotoxin in your mid to late thirties keeps that skin smooth and reduces the risk of lines and jowling. We recommend full face and neck neurotoxin every six months.

For the upper face, generally when you start to see lines that linger after your face relaxes, which is often the late twenties to early thirties. For the lower face and neck, the mid to late thirties is the window where preventative treatment does the most good, because that is when laxity, marionette lines and jowling begin to establish themselves. Prevention is genuinely easier than correction here, since a line etched at rest cannot be erased with toxin alone.

Ready when you are

Dosed properly, from the first visit.

Book directly at Skin! Medical Aesthetics in Denver. We’ll assess your muscles, choose the toxin, quote the dose — and see you again at two weeks to judge the result.